Daryl Powell's side will face newly-promoted Toronto Wolfpack in an 'away' game on Sunday, February 2 at 2.30pm before Leeds host Hull at the same venue at 4.45pm.
The Tigers host Wigan Warriors five days later on February 7 in their first home fixture of the 2020 Super League season.
An away trip to Catalans Dragons awaits eight days later on February 15 in what will be the club's only overseas game until a clash against Toronto Wolfpack in Canada on June 13.
The Tigers host derby rivals Wakefield Trinity on February 21 before ending the month with a trip to Hull KR six days later. Both of those games will be shown live on Sky Sports.
March is set to be a big month for Castleford as they travel to Warrington Wolves on March 6 before hosting Super League holders St Helens on March 15.
They then go to last season's Grand Finalists Salford Red Devils before welcoming rivals Leeds to Wheldon Road on March 26.
The Tigers host Huddersfield Giants on Easter Sunday, April 12, and follow that up with a visit to Belle Vue and Wakefield Trinity on April 17.
Castleford end the season with four home games in their final six fixtures, a run which begins with a home clash against Hull FC on August 7.
They travel to Wigan Warriors a week later before back-to-back home games against Toronto and Warrington Wolves.
A trip to Leeds awaits in the penultimate game of the campaign before the Tigers welcome Huddersfield to Wheldon Road in their final fixture on September 11.
Super League Chief Commercial Officer Rhodri Jones said: “We are delighted to be able to share the full 2020 schedule with our fans, and after a lot of work, we are happy with what has been created.
“Round 1 promises to be a fantastic start to our 25th season with some real heavyweight fixtures.
“There is a new feel to Easter, appreciating the tough nature of Super League on the players, and we’ve kept the Friday night final round of games which proved so successful in 2019.
“There is clearly a lot of excitement with Toronto Wolfpack coming into Super League and we’ve had to work through a number of logistical challenges regarding their fixtures."
Sun 2 Toronto Wolfpack (a) 2.30pm***
Fri 7 Wigan Warriors (h) 7.45pm
Sat 15 Catalans Dragons (a) 5pm
Fri 21 Wakefield Trinity (h) 7.45pm*
Thur 27 Hull KR (a) 7.45pm*
Fri 6 Warrington Wolves (a) 7.45pm*
Sun 15 St Helens (h) 3.30pm
Fri 20 Salford Red Devils (a) 7.45pm
Thur 26 Leeds Rhinos (h) 7.45pm*
Sun 12 Huddersfield Giants (h) 3pm*
Fri 17 Wakefield Trinity (a) 7.45pm
Thur 23 Hull KR (h) 7.45pm*
Sat 2 Hull FC (a) 5pm
Sat 16 Warrington Wolves (a) 3pm
Sat 23 Catalans Dragons** 3pm
Fri 29 Wigan Warriors (h) 7.45pm
Sat 13 Toronto Wolfpack (a) 1.30pm
Fri 19 St Helens (a) 7.45pm
Fri 26 Hull FC (h) 7.45pm
Fri 3 Salford Red Devils (h) 7.45pm
Fri 10 Leeds Rhinos (a) 7.45pm
Fri 24 Catalans Dragons (h) 7.45pm
Fri 31 Huddersfield Giants (a) 7.45pm
Fri 7 Hull FC (h) 7.45pm
Fri 14 Wigan Warriors (a) 7.45pm
Fri 21 Toronto Wolfpack (h) 7.45pm
Fri 28 Warrington Wolves (h) 7.45pm
Fri 4 Leeds Rhinos (a) 7.45pm
Fri 11 Huddersfield Giants (h) 7.45pm
* Sky Sports televised games
** Magic Weekend, Newcastle St James’ Park
***Played at Emerald Headingley Stadium, Leeds