Guiseley suffered defeat at Tranmere Rovers in the National League.
It looked promising for Guiseley when Danny Boshell fired them in front with a long-range effort.
But James Norwood levelled when he headed in Adam Mekki's corner.
And the Rovers striker picked himself up, after a foul by Steven Drench, to net a stoppage-time penalty and deny the visitors a point.
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