Humberside Police said its officers had been at the scene in King Edward Street, where a cordon remains in place.
Nobody is reported to have been hurt but the force is asking members of the public to avoid the area.
A spokesman said: Officers and emergency crews have been at an incident on King Edward St in Hull where a man has been arrested. The area is currently cordoned off.
"We advise that you avoid the area. No one has been hurt."
Also in news: ‘Malign’ teacher who manipulated people into abusing children jailedHe added that more information would be provided when available.