The incident happened on the B6165 Ripley Road in the Nidd area near Knaresborough at 3.25pm on Saturday (July 31).
The motorcyclist was travelling on the road away from Ripley when he collided with a silver Toyota Hilux.
The rider, a man in his 30s, was pronounced dead at the scene.
North Yorkshire Police are now appealing for information from witnesses, and urging people who may have dashcam footage to come forward.
Anyone with information is asked to contact North Yorkshire Police on 101, select option 1 and quote reference 12210171943.
Alternatively email the officer in case, PC Nicola Gill, at [email protected].