The NHS could run out of vital medical supplies quickly as a consequence of the UK crashing out of the European Union without a deal, a hospital boss has warned.
Dr David Rosser, who is the chief executive of the University Hospitals Birmingham NHS Foundation Trust, said that despite stockpiling for Brexit hospitals could face a "completely unprecedented challenge".
The points were raised in a memo to the UHB board of directors last week after being asked to draw up details on readiness for a no-deal Brexit.
Britain is due to leave the European Union on March 29 and MPs voted for Prime Minister Theresa May to return to Brussels to renegotiate parts of the Withdrawal Agreement on Tuesday evening.
In the memo, Dr Rosser said: "In terms of the potential for major operational impact and severe and widespread risks to patient safety, by far the greatest concern is the availability of medicines, devices and clinical supplies."
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He added that the Department of Health and Social Care had identified potential supply shortcomings, but the findings had not been shared with trusts.
Dr Rosser said: "It is assumed that a significant proportion of the medicines and consumables we use at UHB on a daily basis may be at risk."
Staffing is another concern raised in the document, with Dr Rosser writing that UHB employs around 1,200 EU staff, of which 262 are doctors and 375 are nurses or midwives.
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He wrote: "Whilst we have not seen large scale departures so far, it is quite likely that an even more hostile public atmosphere towards Europe in the event of no deal, combined with a further fall in sterling against the euro and other currencies, would affect staff morale and potentially decisions to stay and work in the UK.
"It is difficult to prepare detailed predictions or plans for such unpredictable concerns, however it is difficult to see any scenario whereby a no deal or other chaotic Brexit does not significantly impact our ability to safely treat our patients."