The Reds crashed out of the Champions League last night, and the Whites will be looking to inflict more pain on Jurgen Klopp's side by claiming all three points in their encounter.
Speaking after their loss, Klopp immediately turned his attention to next Monday night, and said: "Monday night against Leeds is the next challenge," Klopp reflected after defeat to Real Madrid.
“The Champions League is very important for this club for different reasons. We can now concentrate on the Premier League. That is what we will do.
“[Leeds are] leading in all the physical stats in the league - we have to run. We have to work our socks off pretty much to get anything but we will try to prepare for it.”
Meanwhile, down in the Championship, a number of Yorkshire's sides remained embroiled in the relegation battle, with Sheffield Wednesday, Huddersfield Town and Rotherham United all in danger of the drop with just a handful of matches left to play.
Here are today's biggest transfer stories and the latest team news involving Leeds United, Barnsley and a number of other sides from Yorkshire and beyond, as the reaction to the build-up to the weekend's action continues:
. LUTON, ENGLAND - APRIL 05: Daryl Dike of Barnsley celebrates after scoring their side's first goal during the Sky Bet Championship match between Luton Town and Barnsley at Kenilworth Road on April 05, 2021 in Luton, England. Sporting stadiums around the UK remain under strict restrictions due to the Coronavirus Pandemic as Government social distancing laws prohibit fans inside venues resulting in games being played behind closed doors. (Photo by Julian Finney/Getty Images)
Leeds United transfer news (Photo by Julian Finney/Getty Images) Photo: Julian Finney
. Forest target to cost £3m
Nottingham Forest transfer target Jacob Murphy is set to cost around £3m this summer. Southampton and Watford look to be the front-runners to sign the Newcastle United winger, who cost them £12m back in 2017. (Football Insider) Photo: STU FORSTER
1. Forest target to cost £3m
Nottingham Forest transfer target Jacob Murphy is set to cost around £3m this summer. Southampton and Watford look to be the front-runners to sign the Newcastle United winger, who cost them £12m back in 2017. (Football Insider) Photo: STU FORSTER
2. Reading could snap up Besic
Reading are said to be lining up a summer swoop for Everton midfielder Mo Besic. The 28-year-old looks set to leave Goodison Park this summer, with his contract expiring at the end of the current campaign. (Telegraph) Photo: Lynne Cameron
3. Palmer expresses fears over Owls' summer
Ex-Sheffield Wednesday star Carlton Palmer has raised his concerns over whether the Owls will be able to overhaul their squad this summer, suggesting players on long-term lucrative deals will be unlikely to agree to an exit. (Transfer Tavern) Photo: Alex Livesey
4. Boro unlikely to keep hold of Kebano
Middlesbrough's hopes of retaining the services of Neeskens Kebano for another season look to have been dealt a blow, with reports claiming he's likely to be in Fulham's plans for next season, especially if they are relegated. (Football League World) Photo: Catherine Ivill