Bloomfield, 40, takes charge of the Hatters after Rob Edwards agreed to step down from the role last week.
He arrives at the Championship from Sky Bet League One promotion hopefuls Wycombe and will be joined by assistant Richard Thomas, first-team coach Lee Harrison and analyst Ben Cirne.
Bloomfield, who has signed a three-and-a-half-year contract, made over 500 appearances for the Chairboys as a player and returned to Adams Park as a manager in 2023 following a stint in charge of Colchester.
But who will now succeed him as manager of Wycombe, a team who are second in League One, four points clear of fourth-placed Huddersfield Town who they lost 1-0 to last Tuesday, and nine clear of Barnsley in fifth.
Here’s a look at the contenders. Odds provided by Bonus Code Bets.
13. 2. Des Buckingham - 9/2
Des Buckingham has previous of getting out of League One with Oxford last season, but lost his job at the end of 2024 (Picture: Bryn Lennon/Getty Images) Photo: Bryn Lennon
14. 1. Claus Norgaard - 3/1
Denmark's Claus Norgaard is currently the assistant head coach at Premier League side Brentford. The 45-year-old is the early favourite for the Wycombe job. (Picture: Christopher Lee/Getty Images) Photo: Christopher Lee