Severe delays after vehicle collides with bridge on major East Yorkshire route
The A63 westbound is now closed between junctions with the A15 near Hull and A1034 at South Cave following the crash.
Highways England said a closure will remain in place for a number of hours.
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Hide AdA vehicle collided with a bridge and debris scattered across the carriageway.
A spokesperson for Highways England said: "Due to the nature of this incident it is anticipated that the closure will remain in place for a number of hours.
"This incident is led by Humberside Police with assistance from Highways England. "